Journal: Computational and Structural Biotechnology Journal

Article Title: Low magnetic fields stimulate cardiac mitochondrial bioenergetics with a bell-shaped response: Possibly via a radical pair mechanism

doi: 10.1016/j.csbj.2025.11.055

Figure Lengend Snippet: Experimental setup for measuring LMF effects on mitochondrial respiration. A: The water jacket of a Hansatech oxygraph was retrofitted with two parallel copper coils mounted on plastic spools, which were connected through the inlet and outlet of the water jacket to a power supply. B: A schematic drawing of the coils (orange color). The average radius of the coil was 1.25 cm. The distance between the centers of the two coils was 2.5 cm, ensuring that the bulk of the chamber was exposed to higher levels of MF generated; however, with a trade-off of non-homogeneous MF inside the chamber. The ends of each coil’s copper wire are connected to a power supply to apply current (I) to the coils. The generated MF direction (red arrow) by applying current (I) and the theoretically calculated MF (B 0 ) strength profile (blue dot curve) were also shown in the graph. C: MF intensities were measured with a Gauss meter every 0.5 cm from the bottom to the top inside the measuring chamber. MF generated by a magnetic stir bar was also measured (blue diamond). The green box shows the ranges of MF (100–150 mA) that produce the most significant effects on mitochondrial O 2 consumption. The table to the right of C shows the average MF magnitude for each applied I, calculated by averaging the measured MF (n = 8) from each location (represented by the data points in each connected curve).

Article Snippet: A: The water jacket of a Hansatech oxygraph was retrofitted with two parallel copper coils mounted on plastic spools, which were connected through the inlet and outlet of the water jacket to a power supply.

Techniques: Generated